Third inoculation, reduction of antibody amount, start of French and German in preparation for mutant strains … Research on “preventive effect 11 times”

Third inoculation, reduction of antibody amount, start of French and German in preparation for mutant strains … Research on “preventive effect 11 times”

The Ministry of Health, Labor and Welfare has decided to give a third booster dose to the new coronavirus vaccine. Even after completing the second vaccination, the amount of antibody that prevents infection will decrease over time, and the aim is to prepare for the emergence of a new mutant virus that is difficult for the vaccine to work.

In Western countries where vaccination preceded, the number of newly infected people increased rapidly due to the influence of the highly infectious mutant virus “Delta strain” derived from India. Since there were a series of “breakthrough infections” in people who completed the second vaccination, Israel, France, and Germany started the third vaccination from those who are likely to become seriously ill after August. The United States and the United Kingdom will also start in the future.

According to an Israeli study, people who received three doses were about 11 times more effective in preventing infection than those who received two doses. However, there is still little data that can be verified. There is also a paper that the effect of preventing aggravation continues for a long time even with two vaccinations.

In Japan, medical workers who started pre-inoculation in February this year have been worried about breakthrough infection half a year after the completion of the two inoculations. The Vaccination and Vaccine Subcommittee held on the 17th decided that the third vaccination was necessary because it might be possible to maintain the effect of the vaccine. However, it is necessary to prepare for the local government, so when and who will start will be discussed in the future.

Professor Junichiro Nishi and Kagoshima University (Infectious Diseases) said, “For the third vaccination, we should continue to monitor the status of breakthrough infections and consider priorities.”

 

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